Think outside of the box and get your mind out of the gutter! 

Homework for Artists and Writers: Draw a 1 - 2 page comic with irregular panel borders.  Avoid working on a grid, avoid right angles, and absolutely no squares or rectangles!

Extra Credit: Think about how a round panel affects the overall effect of your comic.   Jagged shaped panels? Wavy Cloud panels?  Make a note of what works so you can use them later amongst a sea of squares for contrast panels.